Cells phagocytizing bone. Bone metabolism and osteoclast.
نویسندگان
چکیده
منابع مشابه
Regulation of Bone Metabolism
Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...
متن کاملPhysiopathology of Osteoclast in Bone
XIAOMEI GU: Physiopathology of Osteoclast in Bone (Under the direction of Dr. Eric T. Everett) Bone is constantly remodeled by osteoclastic bone resorption and osteoblastic bone formation. Abnormal remodeling can result in bone mass change; bone loss is implicated in a number of bone diseases, representing an increase in bone resorption relative to formation. Therefore, an understanding of oste...
متن کاملregulation of bone metabolism
bone is formed through the processes of endochondral and intramembranous ossification. in endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (mscs) differentiate directly into osteoblasts to form bone. the steps of osteogenic proliferation, differentiation,...
متن کاملOsteoclast-independent bone resorption by fibroblast-like cells
To date, mesenchymal cells have only been associated with bone resorption indirectly, and it has been hypothesized that the degradation of bone is associated exclusively with specific functions of osteoclasts. Here we show, in aseptic prosthesis loosening, that aggressive fibroblasts at the bone surface actively contribute to bone resorption and that this is independent of osteoclasts. In two s...
متن کاملOsteoclast formation from mononuclear phagocytes: role of bone-forming cells
In a previous study, using co-cultures of embryonic bone rudiments stripped of periosteum, and mononuclear phagocytes of various sources, we found that multinucleated mineral-resorbing osteoclasts developed in vitro from radiosensitive mouse bone marrow mononuclear phagocytes (BMMP). (Burger, E. H., J. W. M. van der Meer, J. S. van de Gevel, C. W. Thesingh, and R. van Furth, 1982, J. Exp. Med. ...
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ژورنال
عنوان ژورنال: Kagaku To Seibutsu
سال: 1985
ISSN: 0453-073X,1883-6852
DOI: 10.1271/kagakutoseibutsu1962.23.99